Zerencotrep

MedChem Express

Pico145 [1628287-16-0]

10

1628287-16-0

Research Use Only

99.40

C23H20ClF3N4O5

524.88

Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (?)-englerin A-activated TRPC4/TRPC5 channels, with IC 50 s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8 [1] .

O=C1C2=C(N=C(OC3=CC=CC(OC(F)(F)F)=C3)N2CC4=CC=C(Cl)C=C4)N(C)C(N1CCCO)=O

-20°C,2°C to 8°C

12352200