Pico145 [1628287-16-0]

TargetMol Chemicals

Pico145 [1628287-16-0]

4

1628287-16-0

Chemical

Research Use Only

Pico145

99.06%

C23H20ClF3N4O5

524.88

Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels, specifically inhibiting ( )-englerin A-activated TRPC4/TRPC5 channels with IC50s of 0.349 and 1.3 nM in cells, while showing no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, or TRPM8.

3 years

Cn1c2nc(Oc3cccc(OC(F)(F)F)c3)n(Cc3ccc(Cl)cc3)c2c(=O)n(CCCO)c1=O

-20°C

12352200