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Picropodophyllin [477-47-4]

Picropodophyllin [477-47-4]

Research Use Only
T6943
TargetMol Chemicals
CAS Number477-47-4
Product group Chemicals
Estimated Purity99.41%
Molecular Weight414.41
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Picropodophyllin [477-47-4]
  • Delivery Days Customer
    9
  • CAS Number
    477-47-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Picropodophyllin
  • Estimated Purity
    99.41%
  • Molecular Formula
    C22H22O8
  • Molecular Weight
    414.41
  • Scientific Description
    Picropodophyllin (Picropodophyllin (PPP)) (PPP) is a specific IGF-1R inhibitor (IC50: 1 nM). Picropodophyllin specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with activities of other growth factor receptors, such as receptors for insulin, epidermal growth factor, platelet-derived growth factor, fibroblast growth factor and mast/stem cell growth factor (KIT).
  • Shelf life instruction
    3 years
  • SMILES
    [H][C@]12COC(=O)[C@@]1([H])[C@H](c1cc(OC)c(OC)c(OC)c1)c1cc3OCOc3cc1[C@@H]2O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200