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Pifithrin-alpha, p-Nitro, Cyclic [60477-38-5]

HY-123076
MedChem Express
CAS Number60477-38-5
Product group Chemicals
Estimated Purity98%
Molecular Weight299.35
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Pifithrin-alpha, p-Nitro, Cyclic [60477-38-5]
  • Delivery Days Customer
    10
  • CAS Number
    60477-38-5
  • Estimated Purity
    98%
  • Molecular Formula
    C15H13N3O2S
  • Molecular Weight
    299.35
  • Scientific Description
    Pifithrin-alpha, p-Nitro, Cyclic (PFN-alpha) is cell-permeable and active-form p53 inhibitor. Pifithrin-alpha, p-Nitro, Cyclic is one order magnitude more active than Pifithrin-alpha in protecting cortical neurons exposed to Etoposide (ED50=30 nM). Pifithrin-alpha, p-Nitro, Cyclic behaves as a p53 posttranscriptional activity inhibitor. Pifithrin-alpha, p-Nitro, Cyclic do not prevent p53 phosphorylation on the S15 residue.
  • SMILES
    O=[N+]([O-])C1=CC=C(C2=CN3C(SC4=C3CCCC4)=N2)C=C1
  • Storage Instruction
    -20°C,-80°C
  • UNSPSC
    12352200