Pifithrin-alpha, p-Nitro, Cyclic [60477-38-5]
HY-123076
CAS Number60477-38-5
Product group Chemicals
Estimated Purity98%
Molecular Weight299.35
Overview
- SupplierMedChem Express
- Product NamePifithrin-alpha, p-Nitro, Cyclic [60477-38-5]
- Delivery Days Customer5
- CAS Number60477-38-5
- CertificationResearch Use Only
- Estimated Purity98%
- Molecular FormulaC15H13N3O2S
- Molecular Weight299.35
- Scientific DescriptionPifithrin-alpha, p-Nitro, Cyclic (PFN-alpha) is cell-permeable and active-form p53 inhibitor. Pifithrin-alpha, p-Nitro, Cyclic is one order magnitude more active than Pifithrin-alpha in protecting cortical neurons exposed to Etoposide (ED50=30 nM). Pifithrin-alpha, p-Nitro, Cyclic behaves as a p53 posttranscriptional activity inhibitor. Pifithrin-alpha, p-Nitro, Cyclic do not prevent p53 phosphorylation on the S15 residue.
- SMILESO=[N+]([O-])C1=CC=C(C2=CN3C(SC4=C3CCCC4)=N2)C=C1
- Storage Instruction-20°C,-80°C
- UNSPSC12352200