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ProductsBack/Pifithrin-beta hydrobromide [511296-88-1]

Pifithrin-beta hydrobromide [511296-88-1]

Pifithrin-beta hydrobromide [511296-88-1]

T3637

CAS Number511296-88-1

Product group Chemicals

Estimated Purity99.74%

Molecular Weight349.29

Overview

Supplier
TargetMol Chemicals
Product Name
Pifithrin-bèta hydrobromide
Delivery Days Customer
4
CAS Number
511296-88-1
Category Supplier
Chemical
Certification
Research Use Only
Chemical Name
Pifithrin-bèta hydrobromide
Estimated Purity
99.74%
Molecular Formula
C16H17BrN2S
Molecular Weight
349.29
Scientific Description
Pifithrin-beta hydrobromide (Cyclic PFT-alpha) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of Y therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 microM).
Shelf life instruction
3 years
SMILES
Br.Cc1ccc(cc1)-c1cn2c3CCCCc3sc2n1
Storage Instruction
-20°C
UNSPSC
12352200

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