Pim-1 kinase inhibitor 5 [2928606-67-9]

MedChem Express

Pim-1 kinase inhibitor 5 [2928606-67-9]

14

2928606-67-9

Research Use Only

C22H13Cl2N3O

406.26

Pim-1 kinase inhibitor 5 (Compound 4c) is a Pim-1 kinase inhibitor (IC50: 0.61 microM). Pim-1 kinase inhibitor 5 shows cytotoxicity against cancer cells, with IC50s of 6.95-20.19 microM for HepG2, MCF-7, PC3, and HCT-116 cells[1].

ClC(C(C1=CC(C2=CC=C(OC)C=C2)=NC(Cl)=C1C#N)=C3)=NC4=C3C=CC=C4

12131703