IHC-P analysis of human colon tissue section using GTX00954 PIM1 antibody [GT1192]. Dilution : 1:100
PIM1 antibody [GT1192]
GTX00954
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPIM1
Overview
- SupplierGeneTex
- Product NamePIM1 antibody [GT1192]
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT1192
- ConjugateUnconjugated
- Gene ID5292
- Target namePIM1
- Target descriptionPim-1 proto-oncogene, serine/threonine kinase
- Target synonymsOncogene PIM1; PIM; pim-1 oncogene (proviral integration site 1); proto-oncogene serine/threonine-protein kinase pim-1; serine/threonine-protein kinase pim-1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203