PIM2 Polyclonal Antibody

Reddot Biotech

PIM2 Polyclonal Antibody

5

0.3 mg/ml

PIM2

Pim-2 proto-oncogene, serine/threonine kinase

pim-2 oncogene; pim-2h; proto-oncogene Pim-2 (serine threonine kinase); serine/threonine-protein kinase pim-2

This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity.

-20°C

12352203