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PIM3 Antibody, HRP conjugated

CSB-PA771444LB01HU
Cusabio
ApplicationsELISA
Product group Antibodies
TargetPIM3
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Overview

  • Supplier
    Cusabio
  • Product Name
    PIM3 Antibody, HRP conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    HRP
  • Gene ID415116
  • Target name
    PIM3
  • Target description
    Pim-3 proto-oncogene, serine/threonine kinase
  • Target synonyms
    pim-3; pim-3 oncogene; serine/threonine kinase Pim-3; serine/threonine-protein kinase pim-3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ86V86
  • Protein Name
    Serine/threonine-protein kinase pim-3
  • Scientific Description
    Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression, protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203

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