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PIM447

Research Use Only
HY-19322
MedChem Express
CAS Number1210608-43-7
DownloadMSDS
Product group Chemicals
Estimated Purity99.78
Molecular Weight440.46
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PIM447 [1210608-43-7]
  • Delivery Days Customer
    10
  • CAS Number
    1210608-43-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.78
  • Molecular Formula
    C24H23F3N4O
  • Molecular Weight
    440.46
  • Scientific Description
    PIM447 (LGH447) is a potent, orally available, and selective pan-PIM kinase inhibitor, with Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 displays dual antimyeloma and bone-protective effects. PIM447 induces apoptosis[1][2].
  • SMILES
    O=C(C1=CC=C(F)C(C2=C(F)C=CC=C2F)=N1)NC3=C([C@@H]4C[C@H](C)C[C@H](N)C4)C=CN=C3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200