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PIM447 [1210608-43-7]

PIM447 [1210608-43-7]

Research Use Only
T12475
TargetMol Chemicals
CAS Number1210608-43-7
DownloadMSDS
Product group Chemicals
Molecular Weight440.46
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PIM447 [1210608-43-7]
  • Delivery Days Customer
    14
  • CAS Number
    1210608-43-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    PIM447
  • Molecular Formula
    C24H23F3N4O
  • Molecular Weight
    440.46
  • Scientific Description
    PIM447 is a potent, orally available, and selective inhibitor of pan-PIM kinase(PIM1, PIM2, and PIM3 with Ki values of 6, 18, and 9 pM , respectively).
  • Shelf life instruction
    3 years
  • SMILES
    FC1=C(N=C(C(NC=2C(=CC=NC2)[C@@H]3C[C@H](C)C[C@H](N)C3)=O)C=C1)C4=C(F)C=CC=C4F
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Paíno T et al. The novel pan-PIM kinase inhibitor, PIM447, displays dual anti-myeloma and bone protective effects, and potently synergizes with current standards of care. Clin Cancer Res. 2016 Jul 20.
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