Pimelic Diphenylamide 106

MedChem Express

Pimelic Diphenylamide 106 [937039-45-7]

10

937039-45-7

Research Use Only

98.54

C20H25N3O2

339.43

Pimelic Diphenylamide 106 (TC-H 106) is a slow, tight binding class I HDAC inhibitor (inhibits HDAC1, 2, and 3 with IC50 values of 150 nM, 760 nM, and 370 nM, respectively), with no activity against class II HDACs. Pimelic Diphenylamide 106 modulates dopamine concentration and protects dopamine cells by inducing VMAT2 expression. Pimelic Diphenylamide 106 can be used in the study of neuropsychiatric diseases such as attention deficit hyperactivity disorder (ADHD)[1][2][3].

O=C(NC1=CC=CC=C1N)CCCCCC(NC2=CC=C(C)C=C2)=O

-20°C,2°C to 8°C

12352200