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Pimozide

M2945
AbMole BioScience
CAS Number2062-78-4
Product group Chemicals
Molecular Weight461.55
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Pimozide
  • Delivery Days Customer
    9
  • CAS Number
    2062-78-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C28H29F2N3O
  • Molecular Weight
    461.55
  • Scientific Description
    Pimozide is an antagonist of 6-hydroxyapatide against 6-hydroxyapatide, with Ki values of 1.4 nM, 2.5 nM and 588 nM for 6-hydroxyapatide, D3 and D1 receptors, respectively. Pimozide also has a high affinity for alfa1-adrenoceptor. Ki value is 39 nM. Pimozide is also an inhibitor of STAT3 and STAT5, and piperimidate triggers ADCD in glioblastoma cell lines (LN-229, MZ-54, GOS-3 and U343) by inducing dephosphorylation and inactivation of mTORC1.
  • SMILES
    FC1=CC=C(C=C1)C(CCCN2CCC(CC2)N3C(=O)NC4=CC=CC=C34)C5=CC=C(F)C=C5
  • UNSPSC
    12352200

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