Western blot analysis of extracts of various cell lines using PIN1 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using PIN1 Polyclonal Antibody at dilution of 1:1000.
PIN1 Polyclonal Antibody
E-AB-60610
Product group Antibodies
Overview
- SupplierElabscience
- Product NamePIN1 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionPeptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimers disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.
- UNSPSC12352203