PINK1 antibody [N3C3]
GTX107851
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPINK1
Overview
- SupplierGeneTex
- Product NamePINK1 antibody [N3C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.63 mg/ml
- ConjugateUnconjugated
- Gene ID65018
- Target namePINK1
- Target descriptionPTEN induced kinase 1
- Target synonymsBRPK; PARK6; protein kinase BRPK; PTEN induced putative kinase 1; PTEN-induced putative kinase protein 1; serine/threonine-protein kinase PINK1, mitochondrial
- HostRabbit
- IsotypeIgG
- Protein IDQ9BXM7
- Protein NameSerine/threonine-protein kinase PINK1, mitochondrial
- Scientific DescriptionThis gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Therapeutic effects of the combination of moderate-intensity endurance training and MitoQ supplementation in rats with isoproterenol-induced myocardial injury: The role of mitochondrial fusion, fission, and mitophagy.Read more
- Abnormalities in the SIRT1-SIRT3 axis promote myocardial ischemia-reperfusion injury through ferroptosis caused by silencing the PINK1/Parkin signaling pathway.Read more
- Parkin, as a Regulator, Participates in Arsenic Trioxide-Triggered Mitophagy in HeLa Cells. Zhang Z et al., 2022 Jun 20, Curr Issues Mol BiolRead more
- The nuclear receptor RORalpha preserves cardiomyocyte mitochondrial function by regulating caveolin-3-mediated mitophagy. Beak JY et al., 2021 Dec, J Biol ChemRead more
- Cardiac-specific microRNA-125b deficiency induces perinatal death and cardiac hypertrophy. Chen CY et al., 2021 Jan 27, Sci RepRead more
- Mitochondrial Metabolism as Target of the Neuroprotective Role of Erythropoietin in Parkinsons Disease. Rey F et al., 2021 Jan 15, Antioxidants (Basel)Read more
- The potential LXRbeta agonist stigmasterol protects against hypoxia/reoxygenation injury by modulating mitophagy in primary hippocampal neurons. Haque MN et al., 2021 Jan, PhytomedicineRead more
- Downregulation of Mitochondrial TSPO Inhibits Mitophagy and Reduces Enucleation during Human Terminal Erythropoiesis. Moras M et al., 2020 Nov 28, Int J Mol SciRead more
- Astragaloside IV ameliorates diabetic nephropathy by modulating the mitochondrial quality control network. Liu X et al., 2017, PLoS OneRead more
- NBR1 is dispensable for PARK2-mediated mitophagy regardless of the presence or absence of SQSTM1. Shi J et al., 2015 Oct 29, Cell Death DisRead more