Pinometostat (EPZ5676)

Selleck Chemicals

Pinometostat (EPZ5676) [1380288-87-8]

9

Research Use Only

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Pinometostat (EPZ5676) is an S-adenosyl methionine (SAM) competitive inhibitor of protein methyltransferase DOT1L with Ki of 80 pM in a cell-free assay, demonstrating >37,000-fold selectivity against all other PMTs tested, inhibits H3K79 methylation in tumor. Phase 1.

-80°C

51202000