More than 130 suppliers

In-house tech support

Call +31 (0)26 326 44 50

Bio-Connect

Products
Products
Antibodies
Chemicals
Proteins / Signaling Molecules
Assays
DNA / RNA / Vectors
Cell Culture
Genome Editing and Engineering
Molecular Biology
Lysates / Extracts
Expression
Labware / Accesories
Body Products
Technique Specific Products
Arrays / Slides
Diagnostic
Biologicals
Microbiology
Promotions
All product groups
Support your research
For 15 years, we connect life science researchers specialized in the import and distribution of life science reagents from global suppliers.
How can we help?
Suppliers
Suppliers
Life Sciences
Diagnostics
Services
Become a partner
All Suppliers
Support your research
For 15 years, we connect life science researchers specialized in the import and distribution of life science reagents from global suppliers.
How can we help?
Industries
Industries
Biotech, Pharma & CRO
Academia
Diagnostics
Environment
Food
Veterinary
All industries
Support your research
For 15 years, we connect life science researchers specialized in the import and distribution of life science reagents from global suppliers.
How can we help?
News

Website
Events
Promotions
About us
About us
Our company
Our team
For suppliers
Vacatures
Events
Promotions
Support your research
For 15 years, we connect life science researchers specialized in the import and distribution of life science reagents from global suppliers.
How can we help?
Contact
Contact
Headquarters
Customer Service
Technical support
Accountmanagers
FAQ
Support your research
For 15 years, we connect life science researchers specialized in the import and distribution of life science reagents from global suppliers.
How can we help?

ProductsBack/PION antibody

IHC-P analysis of human brain tissue using GTX32001 PION antibody. Working concentration : 5 microg/ml

IHC-P analysis of human brain tissue using GTX32001 PION antibody. Working concentration : 5 microg/ml

IHC-P analysis of human brain tissue using GTX32001 PION antibody. Working concentration : 5 microg/ml

PION antibody

GTX32001

ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Mouse, Rat

TargetGSAP

Overview

Supplier
GeneTex
Product Name
PION antibody
Delivery Days Customer
9
Application Supplier Note
WB: 0.25 microg/mL. IHC-P: 5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID54103
Target name
GSAP
Target description
gamma-secretase activating protein
Target synonyms
PION, gamma-secretase-activating protein, pigeon homolog, protein pigeon homolog
Host
Rabbit
Isotype
IgG
Protein IDA4D1B5
Protein Name
Gamma-secretase-activating protein
Scientific Description
Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD; MIM 104300). Formation of amyloid-beta is catalyzed by gamma-secretase (see PSEN1; MIM 104311), a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein (APP; MIM 104760) C-terminal fragment (APP-CTF) (He et al., 2010 [PubMed 20811458]).[supplied by OMIM, Nov 2010]
Reactivity
Human, Mouse, Rat
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Datasheet

Download Datasheet

FAQ

Go to our frequently asked questions