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Pitstop 2 [1419320-73-2]

Pitstop 2 [1419320-73-2]

Research Use Only
T26357
TargetMol Chemicals
CAS Number1419320-73-2
Product group Chemicals
Estimated Purity99.53%
Molecular Weight473.36
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Pitstop 2
  • Delivery Days Customer
    4
  • CAS Number
    1419320-73-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Pitstop 2
  • Estimated Purity
    99.53%
  • Molecular Formula
    C20H13BrN2O3S2
  • Molecular Weight
    473.36
  • Scientific Description
    Pitstop2 is an amphipathic protein-bound inhibitor of the clathrin terminal domain (IC50=12 microM) with selectivity. Pitstop2 severely interferes with receptor-mediated endocytosis, HIV entry and synaptic vesicle cycling. Pitstop2 has antitumor activity.
  • Shelf life instruction
    3 years
  • SMILES
    S(NC=1S/C(=C\C2=CC=C(Br)C=C2)/C(=O)N1)(=O)(=O)C=3C4=C(C=CC3)C=CC=C4
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition. von Kleist L et al., 2011 Aug 5, Cell
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