The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA190095(PIWIL2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA190095(PIWIL2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)
PIWIL2 Antibody
CSB-PA190095
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetPIWIL2
Overview
- SupplierCusabio
- Product NamePIWIL2 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID55124
- Target namePIWIL2
- Target descriptionpiwi like RNA-mediated gene silencing 2
- Target synonymsCT80, HILI, PIWIL1L, mili, piwi-like protein 2, cancer/testis antigen 80, piwi-like 2, piwil2-like protein, testicular tissue protein Li 141
- HostRabbit
- IsotypeIgG
- Protein IDQ8TC59
- Protein NamePiwi-like protein 2
- Scientific DescriptionPIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells. Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Plays an essential role in meiotic differentiation of spermatocytes, germ cell differentiation and in self-renewal of spermatogonial stem cells. Its presence in oocytes suggests that it may participate in similar functions during oogenesis in females. Indirectly modulate expression of genes such as PDGFRB, SLC2A1, ITGA6, GJA7, THY1, CD9 and STRA8. Inhibits tumor cell growth when repressed. When overexpressed, acts as an oncogene by inhibition of apoptosis and promotion of proliferation in tumors
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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