PK150

MedChem Express

PK150 [2165324-62-7]

10

2165324-62-7

Research Use Only

99.43

C15H8ClF5N2O3

394.68

PK150, an analogue of Sorafenib, shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits Gram-positive Methicillin-sensitive S. aureus (MSSA), Methicillin-resistant S. aureus (MRSA), Vancomycin intermediate S. aureus (VISA) with MICs of 0.3, 0.3-1, 0.3 microM, respectively [1] .

O=C(NC1=CC=C(OC(F)(F)O2)C2=C1)NC3=CC=C(Cl)C(C(F)(F)F)=C3

-20°C,2°C to 8°C

12352200