PKC-IN-4 [2636771-29-2]
HY-147712
CAS Number2636771-29-2
Product group Chemicals
Molecular Weight379.52
Overview
- SupplierMedChem Express
- Product NamePKC-IN-4 [2636771-29-2]
- Delivery Days Customer10
- CAS Number2636771-29-2
- CertificationResearch Use Only
- Molecular FormulaC21H25N5S
- Molecular Weight379.52
- Scientific DescriptionPKC-IN-4 (compound 7l) is a potent and orally active aPKC inhibitor with an IC50 of 0.52 microM. PKC-IN-4 inhibits TNF-alpha induced NF-kappaB activity in vitro. PKC-IN-4 blocks VEGF- and TNFalpha-induced permeability across the retinal vasculature[1].
- SMILESNCC1CCN(CC1)C2=NC(C3=CC=NC=C3)=NC4=C2C5=C(S4)CCCC5
- UNSPSC12131703