PKCbeta inhibitor 1

MedChem Express

PKCbeta inhibitor 1 [257879-35-9]

9

257879-35-9

Research Use Only

99.40

C24H21N5O2

411.46

PKCbeta inhibitor 1 is a potent, ATP-competitive, and selective PKCbeta inhibitor with IC 50 s of 21 and 5 nM for human PKCbeta1 and PKCbeta2, respectively. PKCbeta inhibitor 1 exhibits selectivity of more than 60-fold in favor of PKCbeta2 relative to other PKC isozymes (PKCalpha, PKCgamma, and PKCepsilon) [1] [2] .

O=C(C(C1=CN(CCCN2C=CN=C2)C3=C1C=CC=C3)=C4NC5=CC=CC=C5)NC4=O

-20°C,2°C to 8°C

12352200