PKCTheta-IN-2

MedChem Express

PKCTheta-IN-2

9

Research Use Only

99.49

C24H23N5O2

413.47

PKCTheta-IN-2 (compound 14) is a potent and selective PKCtheta inhibitor with an IC50 of 0.25 nM. PKCTheta-IN-2 shows good selectivity over a wide range of kinases, including the PKC subfamily (30 kinases). PKCTheta-IN-2 inhibits the IL-2 production in a mouse (IC50 of 682 nM)[1].

C[C@H](C1=CC=CC=C1)N2C3=CC(N4C5=CC=CN=C5NC4=O)=CC=C3C(NC2(C)C)=O

-20°C,2°C to 8°C

12352200