PKMYT1 antibody [1C3]

GeneTex

PKMYT1 antibody [1C3]

9

WB: 1:1000. ICC/IF: 1:100. FACS: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

1C3

1 mg/ml

Unconjugated

PKMYT1

protein kinase, membrane associated tyrosine/threonine 1

MYT1, PPP1R126, membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, myt1 kinase, protein phosphatase 1, regulatory subunit 126

Mouse

IgG2a

Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on Thr-14. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on Tyr-15 to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.

Canine, Human, Rat

-20°C or -80°C,2°C to 8°C

12352203