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PKR-IN-C16 [608512-97-6]

PKR-IN-C16 [608512-97-6]

T16550
TargetMol Chemicals
CAS Number608512-97-6
DownloadMSDS
Product group Chemicals
Estimated Purity0.978
Molecular Weight268.29
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PKR-IN-C16 [608512-97-6]
  • Delivery Days Customer
    4
  • CAS Number
    608512-97-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    PKR-IN-C16
  • Estimated Purity
    0.978
  • Molecular Formula
    C13H8N4OS
  • Molecular Weight
    268.29
  • Scientific Description
    PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures.PKR-IN-C16 binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM. PKR-IN-C16 protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress.
  • Shelf life instruction
    3 years
  • SMILES
    O=C1Nc2ccc3ncsc3c2\C1=C\c1cnc[nH]1
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

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