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PKUMDL-LC-101-D04 [2143896-83-5]

PKUMDL-LC-101-D04 [2143896-83-5]

T36935
TargetMol Chemicals
CAS Number2143896-83-5
DownloadMSDS
Product group Chemicals
Estimated Purity98.71%
Molecular Weight378.94
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PKUMDL-LC-101-D04 [2143896-83-5]
  • Delivery Days Customer
    4
  • CAS Number
    2143896-83-5
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    PKUMDL-LC-101-D04
  • Estimated Purity
    98.71%
  • Molecular Formula
    C14H23ClN4O2S2
  • Molecular Weight
    378.94
  • Scientific Description
    PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4), a regulator of ferroptosis. GPX4 activity was increased to 150% of control levels when used at a concentration of 20 microM in a cell-free assay, and at a concentration of 61 microM in wild-type, but not Gpx4-/-, mouse embryonic fibroblast (MEF) extracts.PKUMDL-LC-101-D04 (200 microM) reduced cholesterol peroxide-induced MEF death.
  • Shelf life instruction
    3 years
  • SMILES
    Cl.NCCNS(=O)(=O)c1ccc(NC(=S)NC2CCCC2)cc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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