PL1601

MedChem Express

PL1601

10

Research Use Only

93.66

C66H83N9O18S

1322.48

PL1601 is a pyrrolobenzodiazepine that can be used as a agent linker of antibody-drug conjugates (ADC)[1]. PL1601 is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

O=C(N([C@H]1O)C(C(C(N2[C@@]1([H])CC(C)=C2)=O)=C3)=CC(OCCCCCOC(C=C(N=C[C@@](C4)([H])N(C=C4C)C5=O)C5=C6)=C6OC)=C3OC)OCC(C=C7)=CC=C7NC([C@H](C)NC([C@H](C(C)C)NC(COCCOCCN[S](NC(OC[C@@H]8[C@@]9([H])[C@]8([H])CCC#CCC9)=O)(=O)=O)=O)=O)=O

-20°C

41115800