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WB analysis of purified human prekallikrein protein (Lane 1) and normal human plasma (Lanes 2 and 3) lysates using GTX21006 Plasma Kallikrein 1B antibody [13G11].
WB analysis of purified human prekallikrein protein (Lane 1) and normal human plasma (Lanes 2 and 3) lysates using GTX21006 Plasma Kallikrein 1B antibody [13G11].
WB analysis of purified human prekallikrein protein (Lane 1) and normal human plasma (Lanes 2 and 3) lysates using GTX21006 Plasma Kallikrein 1B antibody [13G11].

Plasma Kallikrein 1B antibody [13G11]

GTX21006
GeneTex
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetKLKB1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Plasma Kallikrein 1B antibody [13G11]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1-5microg/ml. ELISA: 5-10microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    13G11
  • Conjugate
    Unconjugated
  • Gene ID3818
  • Target name
    KLKB1
  • Target description
    kallikrein B1
  • Target synonyms
    KLK3, PKK, PKKD, PPK, plasma kallikrein, kallikrein B, plasma (Fletcher factor) 1, kininogenin, plasma prekallikrein
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP03952
  • Protein Name
    Plasma kallikrein
  • Scientific Description
    This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Ding C, Scicluna BP, Stroo I, et al. Prekallikrein inhibits innate immune signaling in the lung and impairs host defense during pneumosepsis in mice. J Pathol. 2020,250(1):95-106. doi: 10.1002/path.5354
    Read this paper