WB analysis of purified human prekallikrein protein (Lane 1) and normal human plasma (Lanes 2 and 3) lysates using GTX21006 Plasma Kallikrein 1B antibody [13G11].
WB analysis of purified human prekallikrein protein (Lane 1) and normal human plasma (Lanes 2 and 3) lysates using GTX21006 Plasma Kallikrein 1B antibody [13G11].
Plasma Kallikrein 1B antibody [13G11]
GTX21006
Overview
- SupplierGeneTex
- Product NamePlasma Kallikrein 1B antibody [13G11]
- Delivery Days Customer9
- Application Supplier NoteWB: 1-5microg/ml. ELISA: 5-10microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID13G11
- ConjugateUnconjugated
- Gene ID3818
- Target nameKLKB1
- Target descriptionkallikrein B1
- Target synonymskallikrein B, plasma (Fletcher factor) 1; kininogenin; KLK3; PKK; PKKD; plasma kallikrein; plasma prekallikrein; PPK
- HostMouse
- IsotypeIgG1
- Protein IDP03952
- Protein NamePlasma kallikrein
- Scientific DescriptionThis gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Prekallikrein inhibits innate immune signaling in the lung and impairs host defense during pneumosepsis in mice. Ding C et al., 2020 Jan, J PatholRead more
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