Platensimycin

MedChem Express

Platensimycin [835876-32-9]

10

835876-32-9

Research Use Only

95.00

C24H27NO7

441.47

Platensimycin is an antibiotic produced by S. platensis that inhibits gram-positive bacteria by selectively inhibiting cellular lipid biosynthesis (IC50=0.1 microM). Platensimycin targets the beta-ketoacyl-acyl-carrier-protein synthase I/II, FabF/B, an enzyme that participates in the biosynthesis of fatty acids (IC50s=48 nM and 160 nM for S.aureus and E.coli enzymes, respectively). Platensimycin is a promising agent for overcoming antibiotic resistance.

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-20°C

12352200