Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA866264ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA866264ESR1HU at dilution of 1:100
PLCD4 Antibody
CSB-PA866264ESR1HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetPLCD4
Overview
- SupplierCusabio
- Product NamePLCD4 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID84812
- Target namePLCD4
- Target descriptionphospholipase C delta 4
- Target synonyms1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4; phosphoinositide phospholipase C-delta-4; PLC delta4
- HostRabbit
- IsotypeIgG
- Protein IDQ9BRC7
- Protein Name1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4
- Scientific DescriptionHydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203
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