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PLCH1 antibody [N2C1], Internal

Research Use Only
GTX108612
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetPLCH1
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Overview

  • Supplier
    GeneTex
  • Product Name
    PLCH1 antibody [N2C1], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.93 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID23007
  • Target name
    PLCH1
  • Target description
    phospholipase C eta 1
  • Target synonyms
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1; phosphoinositide phospholipase C-eta-1; phospholipase C-eta1a; phospholipase C-eta1b; phospholipase C-like 3; phospholipase C-like protein 3; PLC eta 1; PLC-eta-1; PLCL3; PLC-L3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ4KWH8
  • Protein Name
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1
  • Scientific Description
    PLCH1 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to generate second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) (Hwang et al., 2005 [PubMed 15702972]).[supplied by OMIM]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Mutations in phospholipase C eta-1 (PLCH1) are associated with holoprosencephaly. Drissi I et al., 2022 Apr, J Med Genet
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  • DNA methylation in demyelinated multiple sclerosis hippocampus. Chomyk AM et al., 2017 Aug 18, Sci Rep
    Read more