ProductsBack/PLCH1 antibody [N2C1], Internal

PLCH1 antibody [N2C1], Internal

Name: PLCH1 antibody [N2C1], Internal
SKU: GTX108612_G10
Availability: BackOrder

GTX108612

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetPLCH1

Overview

Supplier
GeneTex
Product Name
PLCH1 antibody [N2C1], Internal
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.93 mg/ml
Conjugate
Unconjugated
Gene ID23007
Target name
PLCH1
Target description
phospholipase C eta 1
Target synonyms
HPE14, PLC eta 1, PLC-L3, PLCL3, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1, PLC-eta-1, phosphoinositide phospholipase C-eta-1, phospholipase C-eta1a, phospholipase C-eta1b, phospholipase C-like 3, phospholipase C-like protein 3
Host
Rabbit
Isotype
IgG
Protein IDQ4KWH8
Protein Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1
Scientific Description
PLCH1 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to generate second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) (Hwang et al., 2005 [PubMed 15702972]).[supplied by OMIM]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Drissi I, Fletcher E, Shaheen R, et al. Mutations in phospholipase C eta-1 (PLCH1) are associated with holoprosencephaly. J Med Genet. 2022,59(4):358-365. doi: 10.1136/jmedgenet-2020-107237
Read this paper
Chomyk AM, Volsko C, Tripathi A, et al. DNA methylation in demyelinated multiple sclerosis hippocampus. Sci Rep. 2017,7(1):8696. doi: 10.1038/s41598-017-08623-5
Read this paper