Plecanatide

MedChem Express

Plecanatide [467426-54-6]

10

Research Use Only

99.75

Plecanatide, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. Plecanatide activates GC-C receptors to stimulate cGMP synthesis with an EC 50 of 190 nM in T84 cells assay. Plecanatide shows anti-inflammatory activity in models of murine colitis [1] [2] [3] .

-20°C,-80°C

12352202