PLEKHA8 Antibody

Cusabio

PLEKHA8 Antibody

20

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

PLEKHA8

pleckstrin homology domain containing A8

FAPP2, pleckstrin homology domain-containing family A member 8, PH domain-containing family A member 8, phosphatidylinositol 4-phosphate adaptor protein-2, phosphatidylinositol-four-phosphate adapter protein 2, phosphoinositol 4-phosphate adapter protein 2, pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8, serologically defined breast cancer antigen NY-BR-86

Rabbit

IgG

Pleckstrin homology domain-containing family A member 8

Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans-Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation.

Human, Mouse

-20°C or -80°C

41116161