The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA212466(PLEKHG6 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA212466(PLEKHG6 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200)
PLEKHG6 Antibody
CSB-PA212466
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetPLEKHG6
Overview
- SupplierCusabio
- Product NamePLEKHG6 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID55200
- Target namePLEKHG6
- Target descriptionpleckstrin homology and RhoGEF domain containing G6
- Target synonymsARHGEF46, MyoGEF, pleckstrin homology domain-containing family G member 6, PH domain-containing family G member 6, myosin II interacting GEF, myosin interacting guanine nucleotide exchange factor, pleckstrin homology domain containing, family G (with RhoGef domain) member 6
- HostRabbit
- IsotypeIgG
- Protein IDQ3KR16
- Protein NamePleckstrin homology domain-containing family G member 6
- Scientific DescriptionPLEKHG6 functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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