IHC-P analysis of human brain tissue using GTX85229 PLEKHM3 antibody. Working concentration : 5 microg/ml
IHC-P analysis of human brain tissue using GTX85229 PLEKHM3 antibody. Working concentration : 5 microg/ml
PLEKHM3 antibody
GTX85229
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPLEKHM3
Overview
- SupplierGeneTex
- Product NamePLEKHM3 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1 - 2 microg/mL. IHC-P: 5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID389072
- Target namePLEKHM3
- Target descriptionpleckstrin homology domain containing M3
- Target synonymsDAPR; differentiation associated protein; PH domain-containing family M member 3; pleckstrin homology domain-containing family M member 3; PLEKHM1L
- HostRabbit
- IsotypeIgG
- Protein IDQ6ZWE6
- Protein NamePleckstrin homology domain-containing family M member 3
- Scientific DescriptionPLEKHM3, also known as DAPR, is a member of the M family of Pleckstrin homology domain-containing proteins. PLEKHM3 was initially identified through chromatin immunoprecipitation and CpG microarray analysis examining proteins regulated by myocyte-enhancing factor 2. In C2C12 myoblast cells, PLEKHM3 binds to the PI3K signaling member protein kinase B in the cytosol prior to differentiation into myotubes. Following the initiation of differentiation, PLEKHM3 was also found in membrane fractions. Knockdown of PLEKHM3 expression by RNAi resulted in the inhibition of myotube formation, suggesting that PLEKHM3 is a key component required by myoblasts for orchestrating their differentiation during myogenesis.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203