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ProductsBack/Plinabulin [714272-27-2]

Plinabulin [714272-27-2]

Plinabulin [714272-27-2]

T2511

CAS Number714272-27-2

Product group Chemicals

Estimated Purity98.69%

Molecular Weight336.39

Overview

Supplier
TargetMol Chemicals
Product Name
Plinabulin [714272-27-2]
Delivery Days Customer
9
CAS Number
714272-27-2
Certification
Research Use Only
Chemical Name
Plinabulin
Estimated Purity
98.69%
Molecular Formula
C19H20N4O2
Molecular Weight
336.39
Scientific Description
Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM). Plinabulin selectively targets and binds to the colchicine-binding site of tubulin, thereby interrupting equilibrium of microtubule dynamics. This disrupts mitotic spindle assembly leading to cell cycle arrest at M phase and blockage of cell division.
Shelf life instruction
3 years
SMILES
CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2ccccc2)[nH]c1=O
Storage Instruction
-20°C
UNSPSC
12352200

MSDS

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