Bio-Connect

Plogosertib [1137212-79-3]

HY-147298
MedChem Express
CAS Number1137212-79-3
Product group Chemicals
Estimated Purity97.00
Molecular Weight616.80
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    Plogosertib [1137212-79-3]
  • Delivery Days Customer
    10
  • CAS Number
    1137212-79-3
  • Certification
    Research Use Only
  • Estimated Purity
    97.00
  • Molecular Formula
    C34H48N8O3
  • Molecular Weight
    616.80
  • Scientific Description
    Plogosertib (CYC140) is a selective, potent, and orally active ATP-competitive PLK1 inhibitor (IC50: 3 nM). Plogosertib is an anti-cancer agent with anti-proliferative activity. Plogosertib can be used in the research of several tumors, including esophageal, gastric, leukemia, non-small cell lung cancer, ovarian, and squamous cell cancers[1][2].
  • SMILES
    O=C1C2(CC2)CN(C3CCCC3)C4=NC(NC5=C(C=C(C=C5)C(N[C@@H]6CC[C@@H](N7CCN(CC7)C)CC6)=O)OC)=NC=C4N1C
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200