PLpro-IN-8

MedChem Express

PLpro-IN-8

9

Research Use Only

C23H22N2O4

390.43

PLpro-IN-8 (compound 1) is a SARS-CoV papain-like protease (PLpro) inhibitor with IC50 values of 5.9 microM and 0.46 microM for SARS-CoV-2 PLpro and SARS -CoV-1 PLpro, respectively. PLpro-IN-8 inhibits Wuhan strain WK-521 of SARS-CoV-2 with an EC50 of 2.7 microM[1].

C[C@@H](NC(C1=C(C)C=CC(CNC(C(O)=O)=O)=C1)=O)C2=CC=CC3=CC=CC=C32

12352200