Bio-Connect

PLX-4720 [918505-84-7]

HY-51424
MedChem Express
CAS Number918505-84-7
Product group Chemicals
Estimated Purity99.90
Molecular Weight413.83
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PLX-4720 [918505-84-7]
  • Delivery Days Customer
    10
  • CAS Number
    918505-84-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.90
  • Molecular Formula
    C17H14ClF2N3O3S
  • Molecular Weight
    413.83
  • Scientific Description
    PLX-4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-RafV600E than wild-type B-Raf.
  • SMILES
    O=S(NC1=CC=C(C(C(C2=CNC3=NC=C(C=C23)Cl)=O)=C1F)F)(CCC)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200