Bio-Connect

PLX5622 [1303420-67-8]

HY-114153
MedChem Express
CAS Number1303420-67-8
Product group Chemicals
Estimated Purity99.95
Molecular Weight395.41
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PLX5622 [1303420-67-8]
  • Delivery Days Customer
    10
  • CAS Number
    1303420-67-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.95
  • Molecular Formula
    C21H19F2N5O
  • Molecular Weight
    395.41
  • Scientific Description
    PLX5622 is a highly selective brain penetrant and orally active CSF1R inhibitor (IC50=0.016 microM; Ki=5.9 nM). PLX5622 allows for extended and specific microglial cells elimination, preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals. PLX5622 is predominantly administered via ad libitum diets with a dose of 1200 ppm[1][2].
  • SMILES
    COC1=NC=C(F)C=C1CNC2=NC(F)=C(CC3=CNC4=NC=C(C)C=C43)C=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200