Bio-Connect

PLX5622

HY-114153
MedChem Express
CAS Number1303420-67-8
Product group Chemicals
Estimated Purity99.95
Molecular Weight395.41
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PLX5622 [1303420-67-8]
  • Delivery Days Customer
    10
  • CAS Number
    1303420-67-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.95
  • Molecular Formula
    C21H19F2N5O
  • Molecular Weight
    395.41
  • Scientific Description
    PLX5622 is a highly selective brain penetrant and orally active CSF1R inhibitor ( IC 50 =0.016 microM; K i =5.9 nM). PLX5622 allows for extended and specific microglial cells elimination , preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals [1] [2] .
  • SMILES
    COC1=NC=C(F)C=C1CNC2=NC(F)=C(CC3=CNC4=NC=C(C)C=C43)C=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200