PLX5622
HY-114153
CAS Number1303420-67-8
Product group Chemicals
Estimated Purity99.95
Molecular Weight395.41
Overview
- SupplierMedChem Express
- Product NamePLX5622 [1303420-67-8]
- Delivery Days Customer10
- CAS Number1303420-67-8
- CertificationResearch Use Only
- Estimated Purity99.95
- Molecular FormulaC21H19F2N5O
- Molecular Weight395.41
- Scientific DescriptionPLX5622 is a highly selective brain penetrant and orally active CSF1R inhibitor (IC50=0.016 microM; Ki=5.9 nM). PLX5622 allows for extended and specific microglial cells elimination, preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals. PLX5622 is predominantly administered via ad libitum diets. Custom diet of PLX5622 (1200 ppm in AIN-76A) (HY-114153C) is available from MedChemExpress (MCE)[1][2].
- SMILESCOC1=NC=C(F)C=C1CNC2=NC(F)=C(CC3=CNC4=NC=C(C)C=C43)C=C2
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200