Bio-Connect

PLX5622 (hemifumarate)

HY-114153A
MedChem Express
Estimated Purity99.88
Product group Chemicals
Molecular Weight453.45
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PLX5622 (hemifumarate)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    99.88
  • Molecular Formula
    C23H21F2N5O3
  • Molecular Weight
    453.45
  • Scientific Description
    PLX5622 hemifumarate is a highly selective brain penetrant and orally active CSF1R inhibitor ( IC 50 =0.016 microM; K i =5.9 nM). PLX5622 hemifumarate allows for extended and specific microglial elimination, preceding and during pathology development. PLX5622 hemifumarate demonstrates desirable PK properties in varies animals [1] [2] .
  • SMILES
    COC1=NC=C(F)C=C1CNC2=NC(F)=C(CC3=CNC4=NC=C(C)C=C43)C=C2.O=C(O)/C=C/C(O)=O
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200