PLX7683 [1652573-86-8]

TargetMol Chemicals

PLX7683 [1652573-86-8]

72

Research Use Only

PLX7683

C23H19ClF2N4O3S

504.94

PLX7683 is a paradox breaker. Paradox breakers overcame several known mechanisms of resistance to first-generation RAF inhibitors. Dissociating MAPK pathway inhibition from paradoxical activation might yield both improved safety and more durable efficacy than first-generation RAF inhibitors

3 years

CCN(C)S(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(cc23)-c2ccc(Cl)cc2)c1F

-20°C

12352200