PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein)(PMEPA1/2697), CF740 conjugate, 0.1mg/mL
BNC742697
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Proteins / Signaling Molecules
Overview
- SupplierBiotium
- Product NamePMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein)(PMEPA1/2697), CF740 conjugate, 0.1mg/mL
- Delivery Days Customer16
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDPMEPA1/2697
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID56937
- Target namePMEPA1
- Target descriptionprostate transmembrane protein, androgen induced 1
- Target synonymsSTAG1, TMEPAI, protein TMEPAI, solid tumor-associated 1 protein, solid tumor-associated gene 1, transmembrane, prostate androgen induced RNA
- IsotypeIgG
- Scientific DescriptionPMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- Storage Instruction2°C to 8°C,RT
- UNSPSC41116100