PMP22 antibody

GeneTex

PMP22 antibody

9

IHC-P: Use at a dilution of 1/50 for 10 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0 for 10 minutes, followed by cooling at RT for 20 minutes. Optimal dilutions/concentrations should be determined by the end user.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

PMP22

peripheral myelin protein 22

Charcot-Marie-Tooth neuropathy 1A (greatly reduced nerve conduction velocity, hereditary motor sensory neuropathy Ia); CIDP; CMT1A; CMT1E; DSS; GAS3; GAS-3; growth arrest-specific protein 3; HMSNIA; HNPP; peripheral myelin protein 22; peripheral myelin protein 22 kDa; Sp110

Rabbit

IgG

Peripheral myelin protein 22

This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

2°C to 8°C

12352203