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Human Pancreas stained with anti-Peripheral Myelin Protein (PMP-22) antibody (GTX15506)
Human Pancreas stained with anti-Peripheral Myelin Protein (PMP-22) antibody (GTX15506)
Human Pancreas stained with anti-Peripheral Myelin Protein (PMP-22) antibody (GTX15506)

PMP22 antibody

GTX15506
GeneTex
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetPMP22
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Overview

  • Supplier
    GeneTex
  • Product Name
    PMP22 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: Use at a dilution of 1/50 for 10 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0 for 10 minutes, followed by cooling at RT for 20 minutes. Optimal dilutions/concentrations should be determined by the end user.
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID5376
  • Target name
    PMP22
  • Target description
    peripheral myelin protein 22
  • Target synonyms
    Charcot-Marie-Tooth neuropathy 1A (greatly reduced nerve conduction velocity, hereditary motor sensory neuropathy Ia); CIDP; CMT1A; CMT1E; DSS; GAS3; GAS-3; growth arrest-specific protein 3; HMSNIA; HNPP; peripheral myelin protein 22; peripheral myelin protein 22 kDa; Sp110
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ01453
  • Protein Name
    Peripheral myelin protein 22
  • Scientific Description
    This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Dorsal root ganglion application of muscimol prevents hyperalgesia and stimulates myelin protein expression after sciatic nerve injury in rats. Naik AK et al., 2012 Mar, Anesth Analg
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