The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA090243(PNOC Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA090243(PNOC Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)
PNOC Antibody
CSB-PA090243
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetPNOC
Overview
- SupplierCusabio
- Product NamePNOC Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5368
- Target namePNOC
- Target descriptionprepronociceptin
- Target synonymsN/OFQ; nociceptin; nocistatin; NOP; OFQ; orphanin FQ; ppN/OFQ; PPNOC; pre-pro-N/OFQ; prepronociceptin; pronociceptin
- HostRabbit
- IsotypeIgG
- Protein IDQ13519
- Protein NamePrepronociceptin
- Scientific DescriptionNociception, a pain response mechanism, occurs in response to stimuli that threaten the integrity of an organism. The first synapses produced as a result of the initiation of nociception are modulated by excitatory amino acids (glutamate and aspartate) and many peptides (substance P, CGRP, CCK, endogenous opioids). Nociceptin (also designated orphanin FQ) is a neuronal peptide that is similar to opioid peptides. Nociceptin activates KOR-3 (kappa-type opioid receptor, also designated ORL1), a G protein-coupled receptor. Although similar to dynorphin A, a kappa opioid peptide, nociceptin functions to make animals hyperreactive to nociceptive stimulations. Nociceptin is also involved in locomotor behavior and may be involved in the modulation of synaptic plasticity in learning and memory.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203