PNPO antibody [AT2C7]

GeneTex

PNPO antibody [AT2C7]

9

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1:5000. Recommended starting dilution is 1:1000

Western Blot, ELISA

Research Use Only

Monoclonal

AT2C7

1 mg/ml

Unconjugated

PNPO

pyridoxamine 5'-phosphate oxidase

epididymis secretory protein Li 302; epididymis secretory sperm binding protein; HEL-S-302; PDXPO; pyridoxal 5'-phosphate synthase; pyridoxamine-phosphate oxidase; pyridoxine 5'-phosphate oxidase; pyridoxine-5'-phosphate oxidase

Mouse

IgG1

Pyridoxine-5'-phosphate oxidase

The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq, Oct 2008]

-20°C or -80°C,2°C to 8°C

12352203