PNU-142633

MedChem Express

PNU-142633

5

187665-65-2

Research Use Only

98.6

C24H30N4O3

422.52

PNU-142633 is a high affinity, selective and orally active 5-HT1D receptor agonist with Kis of 6 nM and > 18 000 nM for human 5-HT1D receptor and human 5-HT1B receptor, respectively. PNU-142633 has anti-migraine efficacy[1][2].

O=C(C1=CC=C2C(CCO[C@H]2CCN3CCN(C4=CC=C(C(N)=O)C=C4)CC3)=C1)NC

-20°C,2°C to 8°C

12352200