PNU-159682 (GMP) [202350-68-3]
HY-16700G
Overview
- SupplierMedChem Express
- Product NamePNU-159682 (GMP) [202350-68-3]
- Delivery Days Customer14
- CAS Number202350-68-3
- CertificationResearch Use Only
- Molecular FormulaC32H35NO13
- Molecular Weight641.62
- Scientific DescriptionPNU-159682 GMP is a GMP grade PNU-159682 (HY-16700). PNU-159682, a metabolite of the anthracycline Nemorubicin, is a highly potent DNA topoisomerase II inhibitor with excellent cytotoxicity. PNU-159682 acts as a more potent and tolerated ADC cytotoxin than Doxorubicin for ADC synthesis. PNU-159682 can be used in EDV-nanocell technology to overcome agent resistance.
- SMILESCOC1=C(C(C(C(O)=C([C@@H](O[C@H]2C[C@H]3[C@H](O[C@H]4N3CCO[C@@H]4OC)[C@H](C)O2)C[C@@](C(CO)=O)(O)C5)C5=C6O)=C6C7=O)=O)C7=CC=C1
- UNSPSC12352200