Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker) (PDPN/1433), Biotin conjugate, 0.1mg/mL [26628-22-8]

Biotium

Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker) (PDPN/1433), Biotin conjugate, 0.1mg/mL [26628-22-8]

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

26628-22-8

Research Use Only

Monoclonal

PDPN/1433

0.1 mg/ml

Biotin

PDPN

podoplanin

AGGRUS, D2-40, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2, T1A2, TI1A, podoplanin, PA2.26 antigen, T1-alpha, glycoprotein 36, glycoprotein, 36-KD, hT1alpha-1, hT1alpha-2, lung type I cell membrane associated glycoprotein, lung type-I cell membrane-associated glycoprotein (T1A-2)

Mouse

IgG1

Podoplanin

This antibody recognizes a muco-protein of 38-43 kDa, which is identified Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposisarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Human, Mouse

2°C to 8°C,RT

41116161