PODS Human PDGF-AA

Cell Guidance Systems

PODS Human PDGF-AA

999

Western Blot

Research Use Only

PDGFA

platelet derived growth factor subunit A

PDGF-A, PDGF1, platelet-derived growth factor subunit A, PDGF A-chain, PDGF subunit A, platelet-derived growth factor A-chain, platelet-derived growth factor alpha chain, platelet-derived growth factor alpha polypeptide

Platelet-derived growth factor subunit A

The product contains the polyhedrin protein co-crystalized with Human PDGF-AA. Platelet-Derived Growth Factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-?, TGF-? and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the ?-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-a and PDGFR-b.

2°C to 8°C

41116120

Human